Ausgewählte Publikationen

  • Faesen, A.C., M. Thanasoula, S. Maffini, C. Breit, F. Müller, S. van Gerwen, T. Bange, A. Musacchio (2017): Basis of catalytic assembly of the mitotic checkpoint complex. Nature. 542, 498–502.
  • Grüner, B.M., C.J. Schulze, D. Yang, D. Ogasawara, M.M. Dix, Z.N. Rogers, C.H. Chuang, C.D. McFarland, S.H. Chiou, J.M. Brown, B.F. Cravatt, M. Bogyo, M.M. Winslow (2016): An in vivo multiplexed small-molecule screening platform. Nat Methods. 13(10), 883–9. doi: 10.1038/nmeth.3992. PubMedID: 27617390 PMCID: PMC5088491.
  • Javaheri, A., T. Kruse, K. Moonens, R. Mejías-Luque, A. Debraekeleer, C.I. Asche, N. Tegtmeyer, B. Kalali, N.C. Bach, S.A. Sieber, D.J. Hill, V. Königer, C.R. Hauck, R. Moskalenko, R. Haas, D.H. Busch, E. Klaile, H. Slevogt, A. Schmidt, S. Backert, H. Remaut, B.B. Singer, M. Gerhard (2016): Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs. Nat Microbiol. 2, 16189. doi: 10.1038/nmicrobiol. 2016.189.
  • Kalkavan, H., P. Sharma, S. Kasper, I. Helfrich, A.A. Pandyra, A. Gassa, I. Virchow, L. Flatz, T. Brandenburg, S. Namineni, M. Heikenwalder, B. Höchst, P.A. Knolle, G. Wollmann, D. von Laer, I. Drexler, J. Rathbun, P.M. Cannon, S. Scheu, J. Bauer, J. Chauhan, D. Häussinger, G. Willimsky, M. Löhning, D. Schadendorf, S. Brandau, M. Schuler, P.A. Lang, K.S. Lang (2017): Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression. Nat Commun. 8, 14447. doi: 10.1038/ncomms14447.
  • Kim, D.W., R. Mehra, D.S. Tan, E. Felip, L.Q. Chow, D.R. Camidge, J. Vansteenkiste, S. Sharma, T. De Pas, G.J. Riely, B.J. Solomon, J. Wolf, M. Thomas, M. Schuler, G. Liu, A. Santoro, S. Sutradhar, S. Li, T. Szczudlo, A. Yovine, A.T. Shaw (2016): Activity and safety of ceritinib in patients with ALK-rearranged non-small-cell lung cancer (ASCEND-1): updated results from the multicentre, open-label, phase 1 trial. Lancet Oncol. 17(4), 452–63.
  • Klein, J.C., K. Moses, G. Zelinskyy, S. Sody, J. Buer, S. Lang, I. Helfrich, U. Dittmer, C.J. Kirschning, S. Brandau (2017): Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth. Nat Commun. 8, 14600. doi: 10.1038/ncomms14600.
  • Köcher, S., J. Rey, J. Bongard, A.N. Tiaden, M. Meltzer, P.J. Richards, M. Ehrmann, M. Kaiser (2017): Tailored Ahp-cyclodepsipeptides as Potent Non-covalent Serine Protease Inhibitors. Angew Chem Int Ed Engl. 56(29), 8555–8558. doi: 10.1002/ anie.201701771. Epub 2017 Jun 20.
  • Li, M., M. Ehlers, S. Schlesiger, E. Zellermann, S.K. Knauer, C. Schmuck (2016): Incorporation of a Non-Natural Arginine Analogue into a Cyclic Peptide Leads to Formation of Positively Charged Nanofibers Capable of Gene Transfection. Angew Chem Int Ed Engl. 55(2), 598–601. doi: 10.1002/anie.201508714. Epub 2015 Nov 27.
  • McGranahan, N., A.J. Furness, R. Rosenthal, S. Ramskov, R. Lyngaa, S.K. Saini, M. Jamal-Hanjani, G.A. Wilson, N.J. Birkbak, C.T. Hiley, T.B. Watkins, S. Shafi, N. Murugaesu, R. Mitter, A.U. Akarca, J. Linares, T. Marafioti, J.Y. Henry, E.M. Van Allen, D. Miao, B. Schilling, D. Schadendorf, L.A. Garraway, V. Makarov, N.A. Rizvi, A. Snyder, M.D. Hellmann, T. Merghoub, J.D. Wolchok, S.A. Shukla, C.J. Wu, K.S. Peggs, T.A. Chan, S.R. Hadrup, S.A. Quezada, C. Swanton (2016): Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade. Science. 351(6280), 1463–9.
  • Molodtsov, M.I., C. Mieck, J. Dobbelaere, A. Dammermann, S. Westermann*, A. Vaziri* (2016): A Force-Induced Directional Switch of a Molecular Motor Enables Parallel Microtubule Bundle Formation. Cell. 167(2), 539–552. e14, *co-corresponding authors.
  • Petrovic, A., J. Keller, Y. Liu, K. Overlack, J. John, Y.N. Dimitrova, S. Jenni, S. van Gerwen, P. Stege, S. Wohlgemuth, P. Rombaut, F. Herzog, S.C. Harrison, I.R. Vetter, A. Musacchio (2016): Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. Cell. 167, 1028–1040.
  • Schultz, B.T., J.E. Teigler, F. Pissani, A.F. Oster, G. Kranias, G. Alter, M. Marovich, M.A. Eller, U. Dittmer, M.L. Robb, J.H. Kim, N.L. Michael, D. Bolton, H. Streeck (2016): Immunity. Circulating HIV-Specific Interleukin- 21(+)CD4(+) T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions. 44(1), 167–178.
  • Sprengel, A., P. Lill, P. Stegemann, K. Bravo-Rodriguez, E.C. Schöneweiß, M. Merdanovic, D. Gudnason, M. Aznauryan, L. Gamrad, S. Barcikowski, E. Sanchez-Garcia, V. Birkedal, C. Gatsogiannis, M. Ehrmann, B. Saccà (2017): Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions. Nature Communications. 8, 14472.
  • Sucker, A., F. Zhao, N. Pieper, C. Heeke, R. Maltaner, N. Stadtler, B. Real, N. Bielefeld, S. Howe, B. Weide, R. Gutzmer, J. Utikal, C. Loquai, H. Gogas, L. Klein-Hitpass, M. Zeschnigk, A.M. Westendorf, M. Trilling, S. Horn, B. Schilling, D. Schadendorf, K.G. Griewank, A. Paschen (2017): Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions. Nat Commun. 8, 15440. doi: 10.1038/ ncomms15440.
  • van den Boom, J., M. Wolf, L. Weimann, N. Schulze, F. Li, F. Kaschani, A. Riemer, C. Zierhut, M. Kaiser, G. Iliakis, H. Funabiki, H. Meyer (2016): VCP/p97 extracts sterically trapped Ku70/80 rings from DNA in double strand break repair. Mol. Cell. 64, 189–198.
  • von der Ecken, J., S.M. Heissler, S. Pathan-Chhatbar, D.J. Manstein, S. Raunser (2016): Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution. Nature. 534(7609), 724–8.
  • Wang-Gillam, A., C.P. Li, G. Bodoky, A. Dean, Y.S. Shan, G. Jameson, T. Macarulla, K.H. Lee, D. Cunningham, J.F. Blanc, R.A. Hubner, C.F. Chiu, G. Schwartsmann, J.T. Siveke, F. Braiteh, V. Moyo, B. Belanger, N. Dhindsa, E. Bayever, D.D. Von Hoff, L.T. Chen (2016): NAPOLI-1 Study Group. Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial. Lancet. 387(10018), 545–57.