Biomedical Sciences

Selected Publications

  • Budeus, B., S. Schweigle de Reynoso, M. Przekopowitz, D. Hoffmann, M. Seifert, R. Küppers (2015): Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers. Proc Natl Acad Sci U S A. 112(38), E5281–9. doi: 10.1073/pnas.1511270112.
  • Eiteneuer, A., J. Seiler, M. Weith, M. Beullens, B. Lesage, V. Krenn, A. Musacchio, M. Bollen, H. Meyer (2014): Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1. EMBO J. 33(22), 2704–20. doi: 10.15252/embj.201489054.
  • Hyman, D.M., I. Puzanov, V. Subbiah, J.E. Faris, I. Chau, J. Y. Blay, J. Wolf, N. S. Raje, E. L. Diamond, A. Hollebecque, R. Gervais, M. E. Elez-Fernandez, A. Italiano, R. D. Hofheinz, M. Hidalgo, E. Chan, M. Schuler, S.F. Lasserre, M. Makrutzki, F. Sirzen, M.L. Veronese, J. Tabernero, J. Baselga (2015): Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations. N Engl J Med 373(8), 726–36.
  • Khairnar, V., V. Duhan, S. K. Maney, N.Honke, N. Shaabani, A. A. Pandyra, M.Seifert, V. Pozdeev, H. C. Xu, P. Sharma, F. Baldin, F. Marquardsen, K. Merches, E. Lang, C. Kirschning, A.M. Westendorf, D. Häussinger, F. Lang, U. Dittmer, R. Küppers, M. Recher, C. Hardt, I. Scheffrahn, N. Beauchemin, J.R. Göthert, B.B. Singer, P.A. Lang, K.S. Lang (2015): CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production. Nat Commun 6, 6217. doi: 10.1038/ncomms7217.
  • Li, M., S. Schlesiger, S. K. Knauer, C. Schmuck (2015): A Tailor-Made Specific Anion-Binding Motif in the Side Chain Transforms a Tetrapeptide into an Efficient Vector for Gene Delivery. Angew Chem Int Ed Engl. 54(10), 2941–4. doi: 10.1002/anie.201410429.
  • Meesters, C., T. Mönig, J. Oeljeklaus, D. Krahn, C. S. Westfall, B. Hause, J. M. Jez, M. Kaiser, E. Kombrink (2014): A chemical inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thaliana. Nat Chem Biol 10(10), 830–6. doi: 10.1038/nchembio.1591
  • Mieck, C., M. I. Molodtsov, K. Drzewicka, B. van der Vaart, G. Litos, G. Schmauss, A. Vaziri, S. Westermann (2015): Non-catalytic motor domains enable processive movement and functional diversification of the kinesin-14 Kar3. Elife. 27, 4.
  • Poepsel, S., A. Sprengel, B. Sacca, F. Kaschani, M. Kaiser, C. Gatsogiannis, S. Raunser, T. Clausen, M. Ehrmann (2015): Determinants of amyloid fibril degradation by the PDZ protease HTRA1. Nat Chem Biol 11(11), 862–869.
  • Robert, C., B. Karaszewska, J. Schachter, P. Rutkowski, A. Mackiewicz, D. Stroiakovski, M. Lichinitser , R. Dummer, F. Grange, L. Mortier, V. Chiarion-Sileni, K. Drucis, I. Krajsova, A. Hauschild, P. Lorigan, P.Wolter, G. V. Long, K. Flaherty, P. Nathan, A. Ribas, A. M. Martin, P. Sun, W. Crist, J. Legos, S. D. Rubin, S. M. Little, D. Schadendorf (2015): Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib. N Engl J Med. 372(1), 30–9.
  • Saccà B, Y. Ishitsuka, R. Meyer, A. Sprengel, E. C. Schöneweiß, G. U. Nienhaus, C. M. Niemeyer (2015): Reversible Reconfiguration of DNA Origami Nanochambers Monitored by Single-Molecule FRET. Angew Chem Int Ed Engl. 54(12), 3592–7. doi: 10.1002/anie.201408941.
  • Schramm, A., J. Köster, Y. Assenov, K. Althoff, M. Peifer, E. Mahlow, A. Odersky, D. Beisser, C. Ernst, A. G. Henssen, H. Stephan, C. Schröder, L. Heukamp, A. Engesser, Y. Kahlert, J. Theissen, B. Hero, F. Roels, J. Altmüller, P. Nürnberg, K. Astrahantseff, C. Gloeckner, K. De Preter, C. Plass, S. Lee, H. N. Lode, K. O. Henrich, M.Gartlgruber, F. Speleman, P. Schmezer, F. Westermann, S. Rahmann, M. Fischer, A. Eggert, J. H. Schulte (2015): Mutational dynamics between primary and relapse neuroblastomas. Nat Genet 47(8), 872–7.